Obesity increase the risk of carpal tunnel syndrome

Eman A Shakir, Zainab Nazar


Background and Purpose

 Carpal tunnel syndrome (CTS) is one of the furthermost common compression neuropathies of the upper limbs.  Although its etiology is not well unknown, certain disorders are usually associated with CTS, such as diabetes mellitus, obesity, trauma, arthritis, hypothyroidism, amyloidosis, and some types of jobs. We aimed to evaluate the association between the obesity in form of BMI and the severity of nerve conduction impairment in carpal tunnel syndrome patients.


Twenty eight female patients with a clinically and electrophysiological established diagnosis of CTS were incorporated in the study. Their demographic characteristics and severity of CTS were analyzed .Twenty two age matched healthy women were used as control group.


Significant positive correlation between BMI and sensory latency of median nerve was found (p< 0.02)


CTS seems to be more severe in patients with high body mass index.

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- Albers JW, Brown MB, Sima AA, Greene DA. Frequency of median mononeuropathy in patients with mild diabetic neuropathy in the early diabetes intervention trial (EDIT). Muscle Nerve 1996;19:140-6.

- Aroori S, Spence RAJ: Carpal tunnel syndrome. Ulster Med J. 2008, 77: 6-17.

-Becker J, Nora DB, Gomes I, Stringara F, Seitensus R, Panosso JS, Ehlers JAC [2002].

An evaluation of gender, obesity, age and diabetes mellitus as risk factors for carpal tunnel syndrome. Clin Neurophysiol 113(9):1429–1434.

- Bland JD. The relationship of obesity, age, and carpal tunnel syndrome: more complex than was thought? Muscle Nerve 2005; 32:527.

- Franklin GM, Friedman AS. Work-Related Carpal Tunnel Syndrome: Diagnosis and Treatment Guideline. Phys Med Rehabil Clin N Am. 2015 Aug. 26 (3):523-37. [Medline].

-Fujimoto K, Kanchiku T, Kido K, Imajo Y, Funaba M, Taguchi T. Diagnosis of Severe Carpal Tunnel Syndrome Using Nerve Conduction Study and ltrasonography. Ultrasound Med Biol. 2015 Oct. 41 (10):2575-80. [Medline].

- Geoghegan JM, Clark DI, Bainbridge LC, Smith C, Hubbard R. Risk factors in carpal

tunnel syndrome.The Journal of Hand Surgery; British & European Volume. 2004;

(4): 315-20.

- Hendriks, Peter R van Dijk, Klaas H Groenier, et al:Type 2 diabetes seems not to be a risk factor for the carpal tunnel syndrome: a case control study. BMCMusculoskeletal Disorders, 15:346, 2014

-Kerwin G, Williams CS, Seiler JG 3rd. The pathophysiology of carpal tunnel syndrome. Hand Clin. 1996 May. 12(2):243-51.

- MacDermid JC, Wessel J. Clinical diagnosis of carpal tunnel syndrome: a systematic review.J Hand Ther. 2004 Apr-Jun. 17(2):309-19.

- Naik BM, Pal P, Pal GK, Balakumar B, Dutta TK. Assessment of motor nerve conduction in healthy obese Indian population. Int J Clin Exp Physiol 2014; 1: 277-82.

- Nair DS, Dubey DK. Study of median nerve conduction velocity in obesity.Ind J Physiol Pharmac 2006; 52 No. 5: 85.

- Nathan PA, Istvan JA, Meadows KD. A longitudinal study of predictors of research-defined carpal tunnel syndrome in industrial workers: findings at 17 years. J Hand Surg Br 2005; 30:593.

- Nordstrom DL, Vierkant RA, DeStefano F, Layde PM: Risk factors for carpal tunnel syndrome in a general population. Occup Environ Med. 1997, 54: 734-740.

- Padua L, Di Pasquale A, Pazzaglia C, et al. Systematic review of pregnancy-related carpal tunnel syndrome. Muscle Nerve 2010; 42:697.

- Park K. Obesity. In: Park's Text Book of Preventive and Social Medicine. 22 nd ed. Jabalpur: Banarsidas Bhanot Publication; 2013. p. 367-71.

-Shiri R. Hypothyroidism and carpal tunnel syndrome: a meta-analysis. Muscle Nerve 2014; 50:879.

- Shiri R, Pourmemari MH, Falah-Hassani K, Viikari-Juntura E. The effect of excess body mass on the risk of carpal tunnel syndrome: a meta-analysis of 58 studies. Obes Rev. doi. 2015 ;10.1111/obr.12324

-Tosti R, Ilyas AM. Acute carpal tunnel syndrome. Orthop Clin North Am. 2012 Oct. 43(4):459-65. [Medline].

- Yazdanpanah P, Aramesh S, Mousavizadeh A, Ghaffari P, Khosravi Z, Khademi A. Prevalence and severity of carpal tunnel syndrome in women. Iran J Public Health 2012; 41(2): 105-110.

- Yurdakul F1, Bodur H2, Öztop Çakmak Ö3, Ateş C4, Sivas F2, Eser F2, Yılmaz Taşdelen Ö2. On the Severity of Carpal Tunnel Syndrome: Diabetes or Metabolic Syndrome. J Clin Neurol. 2015 Jul; 11(3): 234–240.


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